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Figure 5 outlines our results with non-human primate and human pancreatic sections ( Figure 5 Double-labeling fluorescence IHC of pancreata from healthy humans and those with diabetes showed complete co-localization of the GLP-1R and insulin in all islets and islet-like samples ( Specific expression of the GLP-1R in beta-cells also leads to a high expression in insulinomas (91), indeed, labeled GLP-1R ligands have been suggested as an imaging tool for detection of such tumors (92)

Individual results vary, of course

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These effects may be subtle initially, especially at the lower starting doses

SGLT-2i, sodiumglucose co-transporter-2 inhibitor