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Nat Commun 8 , 14532 (2017)

At 12 weeks, 35% of patients receiving daily stimulation vs 24% of the sham device achieved improvement in the ACR20 endpoint (American College of Rheumatology 20% response criteria)

Weeks Two Through Four Energy levels and recovery speed show the most noticeable regression during this period

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B12 is a water-soluble vitamin essential for neurological function and neurotransmitter regulation, with excess typically excreted in urine