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In addition to the results from SURPASS 4, which was designed to provide preliminary evidence for the cardiovascular safety of tirzepatide, a separate analysis pooling all the clinical trials with tirzepatide was used to generate a pre-specified estimate of cardiovascular events [20] (Table 1)
While this is a key research area, we propose that further investigations should verify whether GLP-1RAs may also affect cognitive and behavioral symptoms seen in psychosis, as suggested by their potential to influence neurobiological (for example, immune function) and neuropsychological (for example, reward) mechanisms that are known to be disrupted in psychotic illness
See What People Are Saying Vitamin D is a supplement that we need when we avoid the sun, as I do
If you miss a dose, follow the specific instructions provided with your medication, which vary by agent
What clinical oversight is in place
Circulation 141:803814
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