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This comprehensive analysis provides new insights into the molecular architecture of RCD pathways and their cooperative functions in maintaining cellular homeostasis

Mutations in the ACOX1 gene result in a very rare autosomal recessive disorder referred to as pseudo-neonatal adrenoleukodystrophy (pseudo-NALD)

10.1016/j.celrep.2019.08.034 238 RosilioC.NeboutM.ImbertV.GriessingerE.NeffatiZ.BenadibaJ.et al

Disruption of this immunological balance may result in persistent inflammation or immunosuppression, hindering tissue regeneration and functional recovery (3235)

sadly, many patients develop severe fatal outcomes because of overwhelming inflammation known as cytokine storm (248, 249), that leads to ROS-mediated cell death and tissue damage typical of RNA viruses (250)

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