Under normal conditions, Nrf2 binds to Keap1 in the cytoplasm, resulting in proteasomal degradation
Houten SM, Wanders RJA, Ranea-Robles P
These results approach the efficacy of Roux-en-Y gastric bypass surgery, which typically produces 25-30% weight loss at one year
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Conventional treatment for OCD relies primarily on specific forms of psychotherapy such as cognitive-behavioral therapy (CBT) and exposure-response prevention therapy, as well as serotonin reuptake inhibitor (SRI) medications (Sudak 2012