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Recommendation: avoid or severely limit alcohol during the first week after each dose increase

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Discussion This study shows that 32 weeks of treatment with semaglutide or empagliflozin, but not combination therapy, is associated with a significant reduction in cortical ADC compared with placebo in a population of patients with type 2 diabetes and high cardiovascular risk

And still I do not blame or shame anyone for being curious about or starting a GLP-1

Acetyl-L-carnitine crosses the blood brain barrier more readily than L-carnitine, has antioxidant properties, and because it has an affinity for nerve cells, may especially provide antioxidant protection for neuronal integrity