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Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties

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a landmark study in the Journal of Investigative Dermatology demonstrated that topical or intraperitoneal thymosin beta-4 increased rat wound reepithelialization by 42% at day 4 and up to 61% at day 7 versus saline controls, with increased collagen deposition and angiogenesis also documented