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Under 90 dB SPL noise exposure, most microglia in both Nrf2-KO mice and control WT mice exposed to pseudo-noise displayed a typical, branched morphology

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But long-term GH replacement therapy (which produces similar GH/IGF-1 levels) has been studied for decades and is considered safe when properly monitored

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In addition to its effects on neurotransmitters, the sleep peptide influences hormonal activity by lowering ACTH levels, which reduces stress-related cortisol production, and by enhancing growth hormone (GH) secretion, essential for restorative sleep

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