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This metabolic adaptation, combined with decreased insulating fat tissue, may create the subjective experience of feeling colder than before treatment initiation
Week 12 showed more substantial progress at 8-9% weight loss, with visible changes in body composition becoming apparent
Combined with slower digestion, meals feel more satisfying with less food
It is a crucial body response to weight loss, with its main purpose being to prevent starvation
In Phase 3 clinical trials, participants started on 2mg once weekly
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