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An active-comparator new-user cohort design is less susceptible to healthy user bias and confounding by indication, because an active treatment with similar indication rather than non-users is the comparator [31, 32]

The South African Health Products Regulatory Authority (SAHPRA), alongside the South African Pharmacy Council (SAPC), recently executed a massive raid on a Pretoria compounding pharmacy

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Presented for research literature review only Lo SC Sr et al

For example, taking Ozempic solely for weight loss would be considered off-label use