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Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and dual GLP-1/gastric inhibitory polypeptide (GIP) receptor agonists (GLP-based therapies) are newer pharmacologic therapies that are used for management of hyperglycemia in type 2 diabetes and are approved for weight loss purposes in the absence of underlying diabetes

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Quantification of GABA A R-1 subunit cluster density was conducted in three structural regions of the DCN: medial, middle, and lateral to cover the tonotopic axis

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Compared with users of basal insulin, GLP-1RA users were younger at index, had less comorbidity, a higher prevalence of use of oral glucose-lowering drugs prior to index and slightly higher education and income levels (Table 1)

It suppresses the IL-6/STAT3 pathway, thereby preventing the HCC cells from inhibiting the cytotoxic effect mediated by natural killer cells (NKs) ( + T cells and induce immunity to tumor rechallenge in Hepa16 allograft mice ( pos CD3 + T cells treated with exendin-4 secreted less IFN-, exhibited weaker migration ability, and upregulated genes related to apoptosis, immunoregulation, and immune deficiency, such as CASP3 and CASP7