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However, if you are sensitive to methylated nutrients or already reacting to supplements, starting with single-ingredient B12 may be safer before introducing a full B-complex
[41] : 973974 Exclusive or near-exclusive breastfeeding beyond six months is a strong indicator of low serum vitamin status in nursing infants
Ongoing inflammatory conditions can affect B12 status
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"Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study"
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