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In all trials, subjects taking semaglutide followed a dose-escalation regimen with the aim of minimizing gastrointestinal adverse events common to the class of GLP-1RAs [23]
The medication's long half-life means that some therapeutic effect persists even after missing one weekly dose, providing a degree of metabolic protection
doi: 10.1111/j.1432-1033.1993.tb17986.x 30 LiuCZouYQianH
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