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2.2.3 Tamoxifen While first considered to be a potential cancer therapy agent due to its ability to inhibit PKC activity (OBrian et al., 1985), tamoxifen later emerged as a drug candidate for mood stabilization given its PKC-inhibiting properties

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After a month on the supplements, elderly (24-month-old) and lethargic rats had more energy and did better on memory tests, while their mitochondria worked better

however, it's important to note that this immediate improvement is often temporary, as the underlying condition still needs time to heal fully