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They are FDA approved primarily for the treatment of type 2 diabetes
A 2025 mini-review on older adults warns that starting and stopping GLP-1s repeatedly can change body composition, sometimes leading to sarcopenic obesity having too much fat and too little muscle
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Plan maintenance before you stop
APOE 4 and Alzheimers disease diagnosis associated differences in L-carnitine, GBB, TMAO and acylcarnitines in blood and brain
Currently, a major gap in the field that applies here relates to the need for a diagnostic biomarker in humans that correlates with pre-neoplastic disease progression (e.g., indicating a high grade PanIN)
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