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TRIUMPH-4 Phase 3 trial Retatrutide and osteoarthritis outcomes

Consultations and record cards

The most common side effects were mild to moderate gastrointestinal issues, with about one-third of patients on the highest orforglipron dose experiencing nausea and about one-quarter experiencing constipation or diarrhea

It is generally not recommended to stop GLP-1 therapy abruptly unless under strict medical supervision

Most patients report feeling fuller faster within the first two weeks, though the scale typically shifts between four and twelve weeks depending on dose, metabolism, and lifestyle factors

Your breasts might get tender, or you might get bigger headaches that may trigger some migraines