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Drucker DJ, Brubaker PL

DeLong MR

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However, possible side effects of indiscriminate STING activation in both healthy and cancerous tissues remain a potential risk that limits their therapeutic index, as mutations that hyperactivate the cGASSTING pathway are known to cause severe autoimmune diseases 16,17

The sample was dried, and peptides were cleaned up with desalting spin columns (Pierce) followed by phosphopeptide enrichment with the High Select Fe-NTA kit (Pierce) according to the manufacturers instructions

Then we pick an injection site, usually your upper arm or hip area