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Biofilm cells exhibit collective phenotypes that differ from planktonic cells including altered metabolism, increased stress response, altered cell surface properties, and the secretion of a protective extracellular matrix (ECM) creating a niche environment, together all these factors contribute to their enhanced tolerance to antifungal therapy and immune clearance (Fanning and Mitchell, 2012

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Common treatments include CPAP therapy, oral appliances, positional therapy, and surgical options

10.1104/pp.15.01543 28 DavalS.LebretonL.GazengelK.BoutinM.Guillerm-ErckelboudtA

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When the liposome reaches a damaged, oxidative-stressed cell, it does not need to rely on complex transport proteins to get inside