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The study included a 26-week treatment period including up to six weeks of dose escalation, followed by a 6-week post-treatment follow-up, extending to week 32

Applications encompass investigating cardiac repair mechanisms, ischemia-reperfusion injury prevention, and heart muscle regeneration pathways

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120 Acetylation of AR at lysine 609 (K609) enhances its binding to enhancer regions of both the AR gene and the ACK1 kinase gene, even in the presence of AR antagonists

However, these changes do not translate to a significant displacement of the cytoplasmic region of TM5