Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey
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Unlike fat-soluble vitamins (A, D, E, and K), which are stored in fat tissue for long periods, water-soluble vitamins are processed relatively quickly: your body takes what it needs, stores a small amount in the liver, and passes most of the rest in urine
If you are currently taking any other medications, let your doctor know before choosing a suitable B12 supplement
It is not associated with any inflammation and is best managed through a rehabilitative approach, offered in conjunction with coping and pacing strategies
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