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FAO generates NADH, FADH2, and acetyl coenzyme A (CoA) in each round, 163 and NADH and FADH2 enter the ETC while the acetyl CoA enters the TCA cycle to produce citrate, which is exported to the cytosol to engage in NADPH production through ME1 and IDH1

456 Additionally, metabolic diseases are often correlated with a series of complications, increasing mortality, and medical costs

implies that combining therapies that reverse defects in keratinocytes metabolism with JAK inhibitors could be a novel approach to treating vitiligo (86)

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Treatment with GABA significantly restores neuron density compared to the model group, as evidenced by the large improvement and the ( p = 0.002), underscoring its neuroprotective effects