Choosing between these two options is a clinical decision that should be made with a healthcare professional
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Between October 5, 2018, and February 1, 2019, 304 individuals were randomly allocated to receive either semaglutide 2.4 mg (n = 152) or placebo (n = 152), with a high trial completion rate of 92.8% (participants attending the end-of-trial safety visit)
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However, panellists also agreed that, in the absence of evidence and clear, consistent guidance, there is a need for an expert-endorsed treatment algorithm, to support clinical decision-making for adults with CKD and T2D
In the phase 3 population PK analysis, only body weight had a relevant effect on the exposure of semaglutide, a finding which did not warrant dose adjustment [12]