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Thus, during SARS-CoV-2 infection, the ensuing antiviral immune and inflammatory responses can change insulin sensitivity, potentially aggravating impairments of glucose metabolism (Fig

In severe dehydration, the kidneys are affected first since they rely on water to filter waste from the blood

The hypoxic environment and the promotion of angiogenesis by hypoxia-inducible factors indicate that oxidative stress may significantly influence synovial tissue [36]

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doi: 10.1016/j.cell.2007.08.036