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With impaired kidney function, accumulation occurs this is a contraindication

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doi: 10.1016/j.vaccine.2014.04.086 258 LymanM.ForsbergK.SextonD

Maximum weight loss usually occurs between months 9-15, with an average total weight loss of 15-20% of initial body weight

The critical rule is maintaining a minimum gap between injections

DAC vs No-DAC Selection This is the single biggest variable