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Pay close attention to digestion, as both hypothyroidism and GLP-1s can slow the gut

Other things you could do is to let your semaglutide pen reach room temperature (since its stored in the refrigerator)

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[6] [7] In the SUSTAIN 7 trial, dulaglutide (Trulicity), a once-weekly injection, demonstrated slightly fewer gastrointestinal adverse events than semaglutide