The influence of age and metformin treatment status on reported gastrointestinal side effects with liraglutide treatment in type 2 diabetes
For severe hypertriglyceridemia (500 mg/dL), fibrates or prescription omega-3 fatty acids (icosapent ethyl) remain first-line to prevent pancreatitis, though GLP-1 therapy may provide additional benefit in appropriate patients
Furthermore, GLP-1 augments mitochondrial efficacy, as manifested by the ameliorated oxidative metabolism of muscle tissue
Primary, adaptive, and acquired resistance to cancer immunotherapy
If you want to try semaglutide for one month before deciding to continue, or if you anticipate needing to pause for surgery, travel, or other reasons shortly after starting, providers offering more flexible subscription structures are a better fit
Conscious of the importance of all the above, we argue for the need of and inquisitive mechanistic and clinically applied research to inform stakeholders about the potential benefits and harms of GLP-1RAs