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In cancer, the delicate balance of proteostasis is often disrupted, leading to the accumulation of misfolded or damaged proteins, aberrant signaling pathways, and genomic instability, all of which contribute to tumorigenesis and cancer progression

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A similar result was also observed in CaSki, a cervical carcinoma cell line naturally infected by HPV16

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Thats reassuring because it suggests this isnt an immune system problem, Friedman says