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Zhang Y, Ding R, Wang S, Ren Z, Xu L, Zhang X, et al

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doi: 10.1212/WNL.56.3.375 22

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Weeks 1-4 Starting dose to assess tolerance Weeks 5-8 First dose increase Weeks 9-12 Therapeutic effects begin Weeks 13-16 Approaching target dose Week 17+ Full maintenance dose Side Effects & Safety Most gastrointestinal side effects are mild, temporary, and occur during the dose escalation period

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Starting at a lower dose allows your body to adapt to GLP-1 receptor activation, reducing the severity of gastrointestinal side effects

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This can cause damage to your DNA, proteins, and cells in your body

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