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That meal causes a much bigger, longer LPS response Your immune system burns a ton of energy fighting that response, which is why you feel sluggish and sleepy after bad meals LPS also binds to LDL particles, makes them harder for the liver to recycle, and they get stuck in artery walls Macrophages arrive thinking it is a bacterial invader

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10.1046/j.1471-4159.1999.0730889.x 16

100 In ER + breast cancer, Dll1-expressing quiescent tumor stem cells activate NotchNF-B signaling to promote survival and resistance to doxorubicin

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The middle third of the thigh, on the front (anterior) or outer (lateral) side