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Moreover, Genistein, by reduction of pro-inflammatory mediators (IL-6, tumor necrosis factor- (TNF-) and C-reactive protein (CRP)) in serum and intestine in alloxan-induced diabetic rats, reduces the damage of L-cells and leads to an increase in the expression and secretion of GLP-1[191]

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Clinically, qualifying for GLP-1 therapy typically requires meeting one of two conditions: a BMI of 30 kg/m or greater, or a BMI of 27 kg/m or greater combined with an obesity-related comorbidity such as type 2 diabetes or cardiovascular risk factors

GHK-Cu is gentler with broader repair benefits