No, and in practice this is not a meaningful factor
A hotel mini-fridge, or the front-desk fridge for short stays, does the job
clockwork web: circadian timing in brain and periphery, in health and disease
Gastrointestinal dopamine as an anti-incretin and its possible role in bypass surgery as therapy for type 2 diabetes with associated obesity
Sikiri, P., Petek, M., Ruman, R., Seiwerth, S., Grabarevi, Z., Rotkvi, I., Turkovi, B., Jagi, V., Mildner, B., Duvnjak, M., Lang, N., Danilovi, Z., Cviko, A., Kolega, M., Sallmani, A., Djai, S., Bura, M., Brki, T., Bani, M.,
NNMT sits on the same one-carbon metabolism that governs SAM, homocysteine and DNA methylation, and the long-term consequences of suppressing it are unstudied