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GSTs catalyze the conjugation of acrolein to GSH and the corresponding conjugate is further modified by the enzymatic cleavage of the GSH glutamic acid and glycine residues by -glutamyltranspeptidase and cysteinylglycinase, respectively
(Marketscreener [42] is based on Reuters.) Regeneron/Hansoh (Jun 2025) Regeneron in-licensed HS-20094 , a Chinese-developed dual GLP-1/GIP agonist now in Phase 3, paying $80M upfront and up to $1.93B in milestones ( [2] )
[7] The discovery of this receptor class preceded the identification of ghrelin, its endogenous ligand, by several years
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