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I use dual incretins quite often in my type one diabetic patients who have obesity and it works beautifully It lessens their insulin requirements Something about that GIP jumpstarts that sluggish pancreas and beta cells However, patients are explicitly told they need to stay on their insulin, watch their sugars closely with CGM and they totally understand
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This thereby hinders the repair of various tissues (151)
(Lupkin, 2025)
Functionally, GLP-1 acts as an important neurotransmitter in peripheral taste coding for the perceptual experience of the sweet [2, 9,10,11,12]
This approach may help keep energy steady and support wellness goals over time
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