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Week 2: reduce to 2.5 mg starter dose

NSAIDs like ibuprofen can irritate the stomach lining directly, and combining this effect with semaglutide's slowed digestion may increase discomfort or nausea in some patients

Hadjadj S, Rosenstock J, Meinicke T, Woerle HJ, Broedl UC

Those with chronic kidney disease should use supplements to increase their magnesium intake

Safety considerations in post-bariatric patients center on gastrointestinal tolerability and nutritional status

GLP-1 medications can be highly beneficial if youre not meeting milestones, especially after nutritional and behavioral interventions have been optimized