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Tirzepatide has a relatively long half-life (approximately five days), which means missing one dose does not reset everything

Other serious side effects of Zepbound to look for include: Blood in urine Allergic reactions Symptoms of low blood sugar (hypoglycemia), including sweating, shaking, dizziness, and hunger, especially in people with Type 2 diabetes Suicidal ideation or suicidal behavior Bottom line: Zepbound constipation is typically mild Based on published clinical trials and healthcare providers experiences, constipation due to Zepbound is typically mild and temporary

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Its something to ask about before increasing your dose, especially if youve already noticed odd skin sensations on Wegovy

It tells your pancreas to release insulin, signals your brain to reduce appetite, and slows the rate at which food leaves your stomach (gastric emptying)

References National Institutes of Health (NIH)