If you're prone to kidney stones or gout, avoid beets or limit how much you eat.
Major cardiovascular outcome trials include: LEADER trial (liraglutide): Demonstrated a significant reduction in major adverse cardiovascular events (MACE) in patients with type 2 diabetes and high cardiovascular risk SUSTAIN-6 (semaglutide): Showed reduced cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke REWIND (dulaglutide): Confirmed cardiovascular benefits across a broad patient population SELECT trial (semaglutide): Showed reduced MACE in people with obesity without diabetes, though this evidence is not yet fully incorporated into UK labelling [17] These trials consistently found that the modest heart rate increases observed did not translate into adverse cardiovascular outcomes
While weight loss can be a positive outcome for diabetics, it can also be dangerous for others who need to maintain their weight for medical conditions
If the litigation progresses to expert testimony and case-specific discovery, juries may not be sympathetic to a company that downplays catastrophic injuries as just a coincidence
Other important adverse effects include: Acute pancreatitis : Severe, persistent abdominal pain radiating to the back requires immediate medical attention
The evidence here is more mixed
