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As mentioned, AOD-9604 is a modified version of the hGH 177-191 fragment, with the only modification being the addition of the amino acid tyrosine at the N-terminus [6]

The molecule is engineered with a trans-3-hexenoic acid moiety covalently attached at the N-terminal tyrosine, a modification that confers significant resistance to enzymatic cleavage by dipeptidyl peptidase-4 (DPP-4)

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Schizophrenia: a concise overview of incidence, prevalence, and mortality

Nijhout HF, Reed MC, Lam S-L, Gregory JF, Shane B, Ulrich CM: In silico experimentation with a model of hepatic mitochondrial folate metabolism