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What GLP-1 drugs actually do GLP-1 therapies do not exaggerate pathological insulin signalling
If your replacement dose stays fixed while your weight drops, you may develop signs of overreplacement: rapid heart rate, anxiety, heat intolerance, or tremor
You want to align your dosage with your lifestylenot fight against it
Its also possible that your health care provider may prescribe it for other reasons not listed here
A 2017 pharmacokinetic modeling study (Kapitza et al., Diabetes Obesity and Metabolism) simulated various dosing intervals for semaglutide and found that intervals between 5 and 9 days produced blood concentration variations within 15% of the target steady-state range
Acknowledgements We would like to thank all JSLE patients and their families for contributing to the pictures in this review and acknowledge colleagues in the Institute of Translational Medicine, Alder Hey Childrens NHS Foundation Trust and the Institute of Integrative Biology, University of Liverpool, Liverpool, UK
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