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Rather, they represent two sides of the same coin, interconnected through the intricate, bidirectional communication network known as the gut-brain axis

For instance, the UPS mediates the targeted degradation of regulatory proteins involved in insulin signaling and lipid metabolism, while autophagy clears damaged organelles such as mitochondria, which are central to energy metabolism

GSH system and ferroptosis in the myocardium Ferroptosis Ferroptosis is a novel form of programmed cell death characterized by the accumulation of iron-catalyzed lipid peroxidation

To further interrogate the underlying dynamics of the Cagri-AMY 3 R complex, relative to rAmy-AMY 3 R complex, we performed molecular dynamics (MD) simulations of Cagri:AMY 3 R:G s and rAmy:AMY 3 R:G s (each system in triplicate, for a total of 6 s)

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