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A defect in homocysteine methyltransferase or a deficiency of B 12 may lead to a so-called "methyl-trap" of THF, in which THF converts to methyl-THF, causing a deficiency in folate

CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (REDEFINE)

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PMID 17892447

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