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A significant interaction between group and time ( 2 (7) = 18.86, p = 0.009, f = 0.39) was found in the linear mixed effects model, revealing that the GLP-1RA group consistently rated their intoxication lower across multiple timepoints compared to the control group (Fig
And yet
This preference resembles that of wild-type BoNT/X, which prefers an arginine at the P11 position in VAMP1 (Extended Data Fig
Research has explored its activity in fatty acid metabolism pathways, mitochondrial function, and cellular energy regulation in controlled laboratory environments
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