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P values are provided within each figure legend, together with the statistical test performed for each experiment: two tailed one-sample, unpaired two-tailed Students t-test or two-way ANOVA followed by post hoc test for multiple comparisons calculated in GraphPad Prism v10.4.2, if not indicated otherwise

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Patients with a history of pancreatitis should be especially cautious about any alcohol consumption while on GLP-1 medications

BMI Requirements: Semaglutide is generally not recommended for individuals with a BMI below 27 unless they have an obesity-related medical condition