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Licensed pharmacological options for weight management in the UK include: Semaglutide (Wegovy, 2.4 mg weekly) a GLP-1 receptor agonist licensed by the MHRA for chronic weight management in adults with a BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity
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[57] demonstrated that GLP-1 based agents were associated with a three-fold increased risk of pancreatic enzyme elevation relative to controls, yet did not indicate a significant rise in pancreatitis or pancreatic cancer
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