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Cold sensitivity usually begins within 2-4 weeks of starting tirzepatide and peaks around weeks 4-8, then improves by weeks 12-16 as your body adjusts

Dosing can be subcutaneous (most common) or intramuscular, localized near the injury or systemic (abdominal)

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Many surgeons recommend approving the use of radiofrequency devices to assist in skin tightening

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