Although the evidence is minimal for the influence of GST polymorphisms of the alpha, mu, pi, and theta classes on susceptibility to various types of cancer, numerous studies have implicated such genotypic variations in asthma, atherosclerosis, allergies, and other inflammatory diseases
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Future research, driven by advanced models, biomarker development, and clinical trials, will pave the way for innovative treatments that balance modulation of angiogenesis with preservation of neuronal homeostasis