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doi: 10.1038/s42003-022-03189-z 211 OuwendijkW
This reflects the biology of GLP-1 regulation and is not necessarily a failure of the medication
Its how much of the actual medicine you are getting
The interaction of these two is common but requires medical attention to ensure safety and reduce the risk of possible side effects
The addition of semaglutide to this already high-risk group showed further b12 decline, but whether this represents a medication effect, dietary changes from additional appetite suppression, or natural progression of post-surgical deficiency remains unclear
The magnitude of benefit, reduced heart attack, stroke, and cardiovascular death, should be balanced against: Common side effects Possible rare harms Cost Individual comorbidities Suppose you have an arrhythmia, heart failure, a history of pancreatitis, or thyroid cancer risk
