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10.1016/j.mad.2008.05.004 122 MannickJ
Even though the immune system responds towards inflammatory stimuli through ROS, increased ROS levels can damage DNA, proteins, and lipids, and result in activating various signaling pathways (such as NF-B and mitogen-activated protein kinase (MAPK)), stimulating T helper cells 1 (Th1) and Th17 cells, and promoting the release of inflammatory cytokines (Plenkowska et al., 2020), which can contribute to the development and exacerbation of the psoriatic inflammation
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Aratrma almalar genellikle deneysel modellerde aadakileri inceleyerek bu bileii aratrmaktadr: Peptid-reseptr etkileim mekanizmalar Hcresel sinyal iletim yolaklarnn dinamikleri Hcre ii dzenleyici alar Molekler sinyal kaskadnn modellenmesi Karlatrmal peptid etkileimi almalar Peptit aracl biyokimyasal dzenleme Deneysel sinyal yolu analizi Bu deneysel modeller, bilim insanlarnn hcresel sinyal iletim davrann ve biyokimyasal yolak etkileimlerini etkileyen molekler dzenleme mekanizmalarn incelemelerine olanak tanr
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