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Adaptation pathways (brainstem nausea circuit, sinus-node baroreflex) respond to rate of change in receptor occupancy
(2017) Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial Janet Vittone, et al
Or, the peptides may not be in a form that can be absorbed by the skin
Journal of Cosmetic Dermatology, 18(3), 728737
(September 2002)
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