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In a study by Ji et al., a novel group of -amino pyrrole-2-carbonitrile analogs was developed as selective DPP-4 inhibitors, with compound 55 (Figure 7) identified as the most potent, exhibiting an IC 50 value of 0.01 M
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Data on the number of prescriptions for and patients using weight-loss drugs came from ClinCalc.com, an online resource for physicians and other health care practitioners
doi: 10.1016/j.apsb.2019.12.006 165 WuXZhuJChenSXuYHuaCLaiLet al
Bottom right, RMSF values plotted on the GLP-1R structure bound to TT-OAD2 (transparent stick representation)
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