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This improvement stems partly from weight loss itselfexcess body weight worsens insulin resistance and inflammation, both of which impair thyroid hormone action at the cellular level

That single finding is what reassured the field that a triple agonist could be both potent and metabolically sensible

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For some midlife women, they can be a helpful part of navigating the very real challenge of menopause weight gain

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For someone who has difficulty getting enough B12 due to underlying health conditions or diet, this helps offset the need for smaller daily increments of B12 from diet or oral vitamins